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Ozempic and similar drugs may lead to blindness Several studies have found that semaglutide-based weight-loss drugs can cause inflammation and restrict blood flow to the eyes. In the U.S., 9 cases with
The prevalence of gastrointestinal adverse events underscores the importance of patient education before initiating semaglutide therapy, including strategies for minimizing discomfort and recognizing warning signs that merit medical attention
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Caspase-mediated ablation of ARC GLP-1R–expressing neurons did not block semaglutide-induced weight loss (123), and CRISPR-mediated GLP-1R knockout in the ARC did not affect acute liraglutide-induced anorexia (125)